Douthat seems to think so:
There might be a bipartisan coalition for a relatively limited measure like the Dream Act, which provides a path to citizenship for college graduates who were brought to America as minors. But if Jeb Bush Republicans and Obama Democrats try to fast track a more comprehensive bill, they will be reminded that there are other sorts of Republicans and Democrats, and that bipartisanship cuts both ways. Even if the president wins re-election, the populist coalition that opposes amnesty may still be as large — if not larger — than the elite coalition that supports it.
But the political elites will be looking for a much bigger future coalition than either of these by passing it. It's a no-brainer for Obama's primary non-economic objective in a second term. And for the campaign.