Nate Cohn imagines the consequences:

If coaches begin to adopt the lessons of advanced football statistics, the changes would be noticeable to even a casual fan: Teams would go for it on fourth down, stop running so much on first down, go for the jugular with a late lead, and take big risks as an underdog in the first quarter. In that sense, statistics might promise more fundamental changes to football than baseball. Fans watching a data-driven baseball manager might not notice any big changes at all, unless they were fans of bunting.