Stuart McMillen has a fascinating new comic on the question. He focuses on the Rat Park research of Bruce Alexander, who compared the drug habits of isolated rats and properly socialized rats. One frame:
McMillen discusses the comic:
I am not denying that certain drugs lend themselves to addictions. Alcohol, heroin and methamphetamines seem to be examples of drugs with properties that allow users to dull reality and escape their troubles, albeit temporarily. However, if the drugs themselves are truly the ’cause’, then by definition everyone who tries these substances should become equally addicted. And that is simply not the case.
Read the entire comic here.