In the current HIV prevention discussion, this idea is well worth airing and perhaps pursuing: Why not put all HIV-negative men on a simple anti-retroviral regimen as a prophylaxis, rather than as a treatment? In any single case, the likelihood of possible transmission drops (because the drugs kill off the virus before it can take hold of a new immune system). The big studies being done will help confirm whether there are collective behavioral adjustments that undermine the effort to reduce transmission. My own view is that gay men, if the studies pan out, could and perhaps should embark on a proactive campaign to get as many sexually active men as possible on meds. It’s a way for HIV-negative men to do something which is not simply defensive in nature, and make decisions about their health in a moment outside the inevitable irrationality of a sexual encounter. We’re used to taking pills after we’ve become sick. Why not take them before – as a prevention technique? Even a mild decline in transmission could drastically alter the dynamic of the epidemic – for the better. Next up: involve vulnerable African-American women in the same discussion.