Christopher Turner remembers the real Bio-Dome. The situation quickly deteriorated, with the bionauts desperate for more food than their meager organic plots could produce. Money quote:
[T]heir memoirs of the two-year project are full of references to their recurring dreams of McDonald’s hamburgers, lobster, sushi, Snickers-bar cheesecake, lox and bagels, croissants, and whiskey.
Although the biosphere was deemed a failure overall, there was one redeeming discovery, thanks to the medic overseeing the team's health:
[Dr. Roy Walford]'s experiments with diet, reported in the Proceedings of the National Academy of Sciences in December 1992, were judged a success. The bionauts not only showed dramatic weight loss (stabilizing at an average of fourteen percent overall), but also lower blood pressure and cholesterol, more efficient metabolisms, and enhanced immune systems.