
Possibly. According to Jens Pruessner, incidence of "anxiety disorders is 21 percent higher for people from the city," and urbanites "have a 39 percent increase for mood disorders." Also, "schizophrenia is almost doubled for individuals who are born and brought up in cities":
Interestingly, it didn't seem to make much difference whether individuals lived in a concrete jungle or a city with a lot of green space. The implication is that it's population density, rather than any other factor, which causes the changes in the brain. Almost 70 percent of the world population is expected to live in a city by 2050, according to United Nations projections.
(Photo by Ludovic Bertron)