Andrew Sprung thinks so:
The delegate math still says Romney, overwhelmingly. But that doesn't mean that the contest doesn't matter. My personal interest is to see Romney pushed to the right, bloodied by intemperate attacks, and exposed as the pseudo-conservative fraud he is for as long as possible. If Alabama and Mississippi can reasonably be taken to indicate that there will be hard-fought primaries from now through June, that's huge news.
R.M. at DiA is on the same page:
[H]ow Mr Romney wins matters. Whether he runs across the finish line in May, or crawls across in June, or successfully negotiates an open convention, will affect his campaign going forward.
The story of the primaries may no longer revolve around whether Mr Romney can be beaten, but the account of his humiliations—like failing to woo his party's base—on his way to victory is just as significant. And the more states Rick Santorum wins, the closer we are to having Mr Romney's would-be coronation degraded to a moment of bitter relief. So far from being a "predictable Republican primary", as Mr Douthat claims, the race is still quite compelling, even if we know who's going to come out on top.
More on Douthat's confidence in Mitt here.
The Dish 