Bruce Bartlett runs the numbers. Ryan says nothing specific about the abolition of tax deductions his plan requires. But it would have to be at least as dramatic as Reagan's in 1986 (something devoutly to be wished but requiring a huge political force). On top of which:
Every governmental function one can think of would be virtually abolished except for Medicare, Social Security and defense.
All because tax rates have to be cut even further. If the GOP could get past that, they'd have an opening. But they can't.