Mo Costandi explains the strange phenomenon of Body Integrity Identity Disorder (BIID), a "rare condition characterized by a burning and incessant desire to amputate an otherwise perfectly healthy limb." Costandi supports giving sufferers the amputations the desire:
Psychotherapy and drugs are completely ineffective in alleviating the condition, and BIID sufferers will go to any length to be rid of the unwanted limb. Some build home-made guillotines, blast their unwanted limbs off with a shotgun, or try lie under a jacked-up car and try to crush it. … Offering a clean surgical amputation to those BIID sufferers who really want it would therefore minimize the harm that they might cause to themselves by taking matters into their own hands.