“I’ll Be A Perfect Fossil”

Humanbody13

Evan R. Goldstein profiles eccentric neuroscientist Kenneth Hayworth. Hayworth is working to create a complete map of a brain's neural circuitry (aka the connectome), and believes brain preservation holds the key to immortality. How he envisions the future procedure:

After Hayworth is placed under anesthesia, a cocktail of toxic chemicals will be perfused through his still-functioning vascular system, fixing every protein and lipid in his brain into place, preventing decay, and killing him instantly. Then he will be injected with heavy-metal staining solutions to make his cell membranes visible under a microscope. All of the water will then be drained from his brain and spinal cord, replaced by pure plastic resin. Every neuron and synapse in his central nervous system will be protected down to the nanometer level, Hayworth says, "the most perfectly preserved fossil imaginable."

His plastic-embedded brain will eventually be cut into strips, perhaps using a machine like the one he invented, and then imaged in an electron microscope. His physical brain will be destroyed, but in its place will be a precise map of his connectome. In 100 years or so, he says, scientists will be able to determine the function of each neuron and synapse and build a computer simulation of his mind. And because the plastination process will have preserved his spinal nerves, he's hopeful that his computer-generated mind can be connected to a robot body.

(Image from the 1959 book The Human Body: What It Is And How It Works via Maria Popova)