Glaswegians have a disturbingly high mortality rate, and researchers haven't been able to explain why:
People have a tendency to blame Glasgow’s peculiar outcomes on whatever they worry about most in Britain today. At last count there were 17 competing explanations for the phenomenon, ranging from the unquantifiable (culture) to the simplistic (not enough vitamin D), via DNA, inequality and history. For this reason, the "Glasgow effect" is also resistant to the remedies peddled by politicians.
What needs explaining is the following: in modern times, up until 1950 Glasgow did not stand out as particularly sickly. But between 1950 and 1980 a gap opened up between it and other big cities in Britain. The difference was mainly explained by a greater number of deaths from cancer and heart disease. Then, starting in about 1980, the gap widened again, though this time the symptoms were different. Glasgow still had too many cancers and heart attacks; but the marked difference from other cities came in deaths from suicide, violence, drug abuse, alcohol and traffic accidents.
As far as the above clip from Trainspotting:
Despite being set in Edinburgh, almost all of the film was filmed in Glasgow, apart from the opening scenes of the film which were filmed in Edinburgh, and the final scenes which were filmed in London.
Another unhealthy scene, in Glasgow:
The Dish 