Performing organ transplants on mice, Japanese researchers tested the effects of different musical genres and artists in improving the outcome of medical procedures. The choice of artist is no small thing:
[T]he mice placed in the silent or the single-frequency rooms suffered from acute graft rejection, as their immune systems rejected the foreign cells from the transplants. Those who had been listening to either Verdi or Mozart showed significantly improved survival outcomes, living an average of twenty days longer. The Enya listeners were not as fortunate: they did little better than the mice who had listened to nothing at all, living just four days longer, on average, than the mice exposed to noise or silence. The authors speculated that what might have been at play are the particular harmonies and musical features of a piece of music.
The human auditory cortex—the part of our brain devoted to hearing and listening—can differentiate between extremely specific frequencies of sound. In fact, single neurons can adjust to barely noticeable frequency shifts at a level that exceeds almost all other mammals (bats are the exception). Music with a four-four tempo, which corresponds closely to a normal heart rate, can help regulate heart rate, circulation, and breathing. Lyrical melodies and rhythms of about sixty to eighty beats a minute, which is common to much classical music and bird song, can stimulate relaxation and alpha brain waves, a type of pattern associated with wakeful relaxation. Yet music that departs from either of those tempos confers none of the benefits.
Previous Dish on the therapeutic uses of music here and here.